Do you really want to stay at a hotel where everybody from the show stays? If so, then enjoy - it can be very beneficial as you will have everyone at your fingertips (quite literally, if you hear the stories about some affiliate manasluts in this industry). That said, as a veteran of countless shows it is nice to stay at some off-the-strip places that provide you some privacy, and enable you to walk through the lobby, to nearby restaurants, etc, without constantly being 'on.' If your meetings are situated properly, you can maximize your efficiency by seeing who you need to meet while still avoiding people that may bog down your personal, independent space. San Francisco is a VERY user-friendly city, and BART is the most efficient public transport in the nation so no matter where you stay you will be within minutes of the Moscone Center.