^As safe as you can be...but the term "Panda/Penguin safe" is generally a marketing gimmick and isn't really within our control. Much of the penalties came from people hitting their sites with the same anchor text over and over, so if you choose to do that then there's nothing we can do about it.
There are about a dozen IPs. Most SEO hosting uses unique IPs, and we moved away from that because those hosts are easily targeted by G for de-indexation. Our sites are hosted at 'normal' shared hosting datacenters so that they blend in with the millions of other sites hosted like that.